Aesthetic Medicine

Migraine Treatment with Botulinum Toxin

Therapeutic Botox for Chronic Migraine Relief

Migraine Treatment with Botulinum Toxin

About This Treatment

For patients living with chronic migraine — 15 or more headache days per month, eight of which are migrainous — therapeutic botulinum toxin (Botox) is one of the most effective, evidence-based treatments available. Approved specifically for chronic migraine prevention, Botox reduces both the frequency and intensity of headaches by calming the nerves and muscles that contribute to migraine generation.

The treatment follows the PREEMPT protocol, an internationally validated injection scheme that places small doses of botulinum toxin across 31-39 specific points on the forehead, temples, back of the head, neck, and shoulders. Rather than a cosmetic application, this is a precise neurological intervention performed by physicians trained in migraine medicine.

At Alpha Medical Limassol, migraine Botox is one of the most requested therapeutic services, with patients travelling from across Cyprus and abroad. The treatment is also available at our Tel Aviv and Dubai clinics under the same physician-led standards.

Key Benefits

Proven Migraine Reduction

Clinical studies show significant reduction in migraine days for chronic sufferers within 2-3 treatment cycles.

Fewer Medications

Many patients are able to reduce or discontinue daily preventative medications with their physician's guidance.

Long-Lasting Effect

Each treatment cycle lasts approximately 12 weeks, with effects maintained through repeat treatments.

Minimal Side Effects

Well tolerated by most patients, with minimal systemic effects compared to oral medications.

Improved Quality of Life

Patients report better work, family and social functioning once migraine frequency decreases.

Complements Other Care

Can be safely combined with oral preventatives, CGRP inhibitors and lifestyle interventions.

The Treatment Process

1

Neurological Consultation

A thorough assessment confirms the diagnosis of chronic migraine and rules out other causes of headache.

2

PREEMPT Protocol Injections

Your physician administers 155-195 units of botulinum toxin across 31-39 injection points using the validated PREEMPT protocol.

3

Follow-Up at 4-6 Weeks

We review your migraine diary to assess response, tolerability, and plan any adjustments for the next cycle.

4

Quarterly Treatment Cycles

Treatment is repeated every 12 weeks. Most patients achieve maximum benefit after 2-3 cycles.

Ideal For Treating

Chronic migraine (15+ headache days/month)
Migraine with or without aura
Patients who have failed oral preventatives
Patients seeking to reduce medication burden
Tension-component headaches
Medication-overuse headache (with withdrawal support)
Patients who cannot tolerate CGRP inhibitors
Long-term migraine sufferers seeking better control

Where We Practice

Migraine Treatment with Botulinum Toxin Across Three Clinics

Alpha Medical delivers Migraine Treatment with Botulinum Toxin at the same physician-led standard across all our locations. Our flagship clinic is in Limassol, Cyprus, with partner clinics in Tel Aviv and Dubai for patients who travel between regions.

Flagship

Limassol, Cyprus

Our Limassol clinic is the primary centre for Migraine Treatment with Botulinum Toxin, serving patients from across Cyprus — including Nicosia, Larnaca, and Paphos — as well as international patients.

Book in Limassol →

Partner Clinic

Tel Aviv, Israel

Migraine Treatment with Botulinum Toxin is also available at our Tel Aviv location, with the same physician-led protocols and clinical standards.

Enquire about Tel Aviv →

Partner Clinic

Dubai, UAE

Our Dubai location delivers Migraine Treatment with Botulinum Toxin under the same Alpha Medical standards for patients based in or travelling through the Gulf.

Enquire about Dubai →

Frequently Asked Questions

Additional Information

Request More Information About Migraine Treatment

Leave your details and our team will send you an introductory overview by email, then reach out personally. You are welcome to contact us directly on WhatsApp at any time.

Migraine Treatment

Additional Information About Migraine Treatment

Enter your details and we will send you an introductory guide about Migraine Treatment by email. Our clinical team will follow up with you personally.

Prefer to chat now? Message us directly on WhatsApp.

Ready to Begin?

Schedule a private consultation with our skin specialists to discuss how Migraine Treatment with Botulinum Toxin can help you achieve your aesthetic goals.

Medical Disclaimer: Results vary between individuals. All treatments are performed by qualified medical professionals. A consultation is required to assess your suitability for any procedure. The information on this page is for educational purposes and does not constitute medical advice.